The spine is one of the common sites for bone metastasis of malignant tumors, and vertebral body metastasis is more common. Bone destruction caused by metastatic tumors often leads to vertebral collapse or deformity, spinal cord compression, pathological fractures, hypocalcemia, and secondary hyperparathyroidism, causing severe pain and dysfunction, seriously affecting the quality of life of patients , to shorten the lifetime.
Conventional symptomatic treatment includes oral analgesics, palliative radiotherapy, surgery, and systemic therapy such as bisphosphonates. Many patients struggle with these treatments due to repeated visits, poor efficacy and side effects. In 1984, French surgeon Galibert reported the application of percutaneous bone cement injection in the treatment of intractable pain caused by the second hemangioma of the cervical spine, creating a precedent for minimally invasive percutaneous bone cement injection in the treatment of vertebral lesions. Within 48 hours of percutaneous vertebroplasty (PVP) or percutaneous balloon kyphoplasty (PKP), significant pain relief was associated with reduced medication use and improved functional parameters.
